Perhaps the most remarkable also strong influence it has on the human body is its ability to cause hyperplasia, which is an definite splitting of cells. Hypertrophy is what ensues during weight training; it is an increase in the size of muscle cells. Adult humans have a fixed number of muscle cells, that can become larger with training, however the number of muscle cells does not increase. But, with this preparation use you are able to induce hyperplasia which actually increases the number of muscle cells present in the muscle. Research studies show that with weight training the new cells develop faster and become stronger and more dense. What is IGF - 1 IGF-1 (Insulin-like Growth Factor-1) is a polypeptide compound produced from HGH (Human Growth Hormone). IGF stands for insulin-like growth factor. Among the effects the most positive are increased amino acid transport to cells, increased glucose transport, increased protein synthesis, and decreased protein degradation. When IGF is active it behaves differently in different types of tissues. In muscle cells, proteins and associated cell components are stimulated. Protein synthesis is increased along with amino acid absorption. As a source of energy, IGF mobilizes fat for use as energy in adipose tissue. In lean tissue, IGF prevents insulin from transporting glucose across cell membranes. As a result the cells have to switch to burning off fat as a source of energy. IGF-I builds new muscle tissue by promoting nitrogen retention and protein synthesis. This causes the growth of muscles through both hyperplasia (which is an increase in number of muscle cells) and mitogenesis (which is the actual growth of new muscle fibers). Thus IGF-I not only makes muscle fibers bigger, it makes more of them as well. IGF-I is a peptide roughly the same structure and size as insulin, or about 70 amino acids long. It belongs to the peptide family of substances identified as growth factors. It is a hormone released in the liver as well as in peripheral tissues such as skeletal muscle. In the body, IGF-I is released in response to the presence of Human Growth Hormone (HGH). After intense resistance training, the body experiences a surge in GH and IGF, and this is one way that new muscle is built. Although GH is considered to be highly anabolic, in actuality, IGF-I is suspected to be responsible for the primary anabolic activities of GH. IGF-I builds new muscle tissue by promoting nitrogen retention and protein synthesis. This causes the growth of muscles through both hyperplasia (which is an increase in number of muscle cells) and mitogenesis (which is the actual growth of new muscle fibers). Thus IGF-I not only makes muscle fibers bigger, it makes more of them as well! Effects IGF-IÃ¢â‚¬â„¢s effects are not limited to building new muscle, however. It has a potent effect on lipid (fat) metabolism, and helps the body burn fat at a significantly elevated rate. In addition, IGF-I is both a neuroprotector and neuropromotor, which improves mental functions such as reflexes, memory, and learning ability. IGF is also important for production of connective tissue and insuring proper bone density. High IGF-I levels are correlated with higher levels of lean body mass. Neuroprotective, myelinatory, synaptogenic, and anti-catabolic effects of IGF-I are well-documented in human and animal study subjects. Serum IGF-I levels correlate positively to higher IQ in children. Suggested Usage Shake well before use. 1cc in mouth, hold 90 seconds and then swallow. Consume 1-2 times per day.